When faced with an infection caused by Helicobacter pylori , which can cause heartburn, nausea or even ulcers, antibiotics are often a necessary step.
However, certain probiotic strains can be a smart complement to medical treatment for improved digestive comfort . But which ones should you choose, and how do they work ? Science sheds light on their true effectiveness.
Key takeaways:
- Complementary role: Probiotics do not replace antibiotics, but help to reduce their side effects and rebalance the intestinal flora.
- Specific strains: Only certain strains such as Lactobacillus reuteri , Saccharomyces boulardii and Lactobacillus rhamnosus GG have studied efficacy against H. pylori.
- Better tolerance: They significantly improve tolerance to eradication treatment by reducing digestive disorders such as diarrhea.
- Overall support: In addition to their targeted action, the benefits of probiotics strengthen the intestinal barrier and general immunity.
Helicobacter pylori: what are we talking about?
Helicobacter pylori is a very resistant bacterium capable of colonizing the lining of the stomach, an extremely acidic environment.
Its presence is not always symptomatic , but in some people it can lead to chronic inflammation of the stomach ( gastritis ), gastric pain, reflux, indigestion, and in more severe cases, gastroduodenal ulcers.
The standard treatment to eradicate this bacterium is a combination of antibiotics and a powerful antacid (proton pump inhibitor). This is known as triple or quadruple therapy, protocols that can be demanding and accompanied by side effects.
What is the role of probiotics against Helicobacter pylori?
Probiotics, defined by the WHO as " live microorganisms which, when administered in adequate amounts, confer a health benefit on the host ", are not an eradication treatment in themselves.
Their role is primarily that of an intelligent facilitator , acting on several fronts:
- Restoring the gut microbiota: Antibiotic treatments, while necessary, do not differentiate between "good" and "bad" bacteria, thus disrupting the balance of the gut microbiota . Probiotics help to repopulate the gut with beneficial bacteria.
- Reduced side effects: One of the most documented benefits is the reduction of side effects associated with antibiotics, such as diarrhea, abdominal pain, or taste disturbances. (source: Romain Kimmel )
- Direct action on H. pylori: Certain probiotic strains, such as Lactobacillus reuteri , have demonstrated an ability to produce substances that inhibit the growth of H. pylori. They can also compete with the bacteria for space and nutrients on the stomach lining.
- Immune support: Probiotics help strengthen the intestinal barrier and modulate the body's immune response, which is an asset in the fight against chronic infection.
Our expert solution
For comprehensive microbiota support, our Supernutrition Probiotics Intestinal Flora product may be relevant.
Discover Probiotics for Gut FloraWhich probiotic strains have shown an effect against Helicobacter pylori?
Not all probiotic strains are equally effective against H. pylori. Scientific research has focused on very specific strains, identified by their full name (genus, species and strain designation).
Lactobacillus reuteri
This is one of the most studied strains in this context. Several studies , particularly on the DSM 17938 and ATCC PTA 6475 strains, show that it can reduce the bacterial load of H. pylori and significantly improve gastrointestinal symptoms as well as treatment tolerance.
Saccharomyces boulardii
This probiotic yeast is particularly known for mitigating the side effects of antibiotic treatments, especially diarrhea . When combined with triple therapy, it results in better overall tolerance and a slight increase in the eradication rate.
Lactobacillus rhamnosus GG
This strain is well known for its beneficial effects on the balance of the gut flora and the strengthening of the immune system . It helps to stabilize the intestinal microbiota during antibiotic treatment.
Bifidobacterium bifidum & breve
These beneficial bacteria, often found in combination with other strains, contribute to overall gut health. The Bifidobacterium genus has been associated with a lower incidence and less severe side effects from eradication therapy.
How to integrate probiotics into the management of H. pylori?
During or after antibiotic treatment?
Both approaches are beneficial. Taking it during antibiotic treatment (by delaying the dose by a few hours to prevent the antibiotic from destroying the probiotic) mainly helps to limit side effects.
Continuing the treatment after the end of antibiotics is crucial for the long-term restoration of gut flora. Some studies suggest that administration started before and continued during treatment offers the best results.
Minimum treatment duration
A course of treatment lasting at least 2 to 4 weeks is recommended to observe beneficial effects. For a thorough restoration of the gut microbiota after a course of antibiotics, it is often advised to continue treatment for several weeks.
On an empty stomach or with meals?
It depends on the product's formulation. For non-gastro-resistant capsules, it is often recommended to take them with a meal so that the food protects the bacteria from stomach acid. If the capsules are gastro-resistant, they can be taken on an empty stomach.
Importance of dosage
The effectiveness of a probiotic depends on the quantity of live microorganisms it contains, expressed in CFU (Colony Forming Units). The dosages studied are often several billion CFU per day.
The limitations of probiotics you should know
It is essential to keep several key points in mind:
- Probiotics are never a substitute for medical treatment: H. pylori infection can have serious consequences and must be treated with antibiotics prescribed by a doctor.
- A proven support role: Their effectiveness has been demonstrated in improving tolerance and supporting the body, but no study proves that probiotics alone can eradicate the bacteria.
- Seek advice from a healthcare professional: Before starting any treatment, it is essential to seek the advice of your doctor or pharmacist, especially in the case of an ulcer, serious illness or weakened immune system.
In short: helpful support, but not a miracle solution
In conclusion, the integration of specific probiotics in the management of Helicobacter pylori infection is a scientifically validated and relevant strategy .
They can significantly reduce digestive symptoms and improve tolerance to antibiotic treatment . Strains such as Lactobacillus reuteri DSM 17938 and Saccharomyces boulardii have demonstrated an effect when used in conjunction with eradication therapy.
Use them wisely, as a valuable complement to appropriate medical monitoring, to give yourself every chance.
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