Key takeaways
- Nutri&Co uses 2 patented SynbAEctive® complexes supported by published clinical studies and adds vitamin B2, the only authorized European health claim for this type of formula.
- Noobiotik has the highest total volume of the three: 25 billion CFUs per dose, with the codes for its 5 strains published.
- Our Intimate Flora Probiotics concentrate L. crispatus at 10 billion CFUs, which is 67% more than Nutri&Co and 43% more than Noobiotik.
- L. helveticus, documented for its activity against Candida albicans, is absent from the Nutri&Co and Noobiotik formulas.
Nearly 75% of women experience at least one episode of vaginal candidiasis before menopause 1. Nutri&Co and Noobiotik dominate searches in this segment. We compared their formulas strain by strain.
Nutri&Co, Noobiotik, SuperNutrition: the complete comparison
All three formulas target the vaginal microbiota orally with gastro-resistant capsules. Their compositional choices differ radically.
| Criterion | Nutri&Co | Noobiotik | SuperNutrition |
|---|---|---|---|
| Monthly price | €19.90 | €29.90 | €21.90 |
| CFU per dose | 12 Billion | 25 Billion | 20 Billion |
| L. crispatus | 6 Billion (CCFM1110) | 7 Billion (CNCM I-5095) | 10 Billion |
| L. helveticus | Absent | Absent | 2.5 Billion |
| Patented complexes | SynbAEctive® Femme + Gynelle | None | None |
| Vitamin B2 | 0.21 mg (15% RI) | Absent | Absent |
| Capsules per day | 2 | 2 | 1 |
| Published strain codes | Yes | Yes | Online analysis certificates |
| Origin L. crispatus | Shanghai, China | France (INRAE) | France |
| Number of customer reviews | 1,163 (4.6/5) | 130 (4.8/5) | 69 (4.8/5) |
| Pharmacy distribution | Yes | No | No |
The monthly price puts Nutri&Co in the lead, with a €10 difference compared to Noobiotik for a one-month course. Over a three-month course, this difference reaches €30.
Nutri&Co Intimate Flora: the strength of patented complexes
Nutri&Co builds its formula around two patented complexes developed by the Italian laboratory SynBalance: SynbAEctive® Femme and SynbAEctive® Gynelle. These complexes combine four codified strains totaling 4 billion CFUs.
What SynbAEctive® clinical studies show
A clinical study conducted on 75 patients suffering from recurrent bacterial vaginosis evaluated the SynbAEctive® Femme complex (L. plantarum PBS067, L. rhamnosus LRH020, B. animalis lactis BL050) for 14 consecutive days, then 7 days per month for 4 months 2.
The supplemented group showed a recurrence rate of 16% compared to 40% in the control group. pH, the proportion of clue cells, discharge, and odor improved across all evaluated criteria.
An observational study published in 2024 in the journal Nutrients also evaluated these same strains in postmenopausal women, with favorable results on the composition of the vaginal microbiota 3.
16% vs 40%: bacterial vaginosis recurrence rate in the SynbAEctive® Femme group compared to the control group over 4 months of supplementation 2.
Vitamin B2, the only authorized health claim in this segment
Nutri&Co adds 0.21 mg of riboflavin, or 15% of the reference intake. Vitamin B2 contributes to the maintenance of normal mucous membranes: this is the only health claim validated by European regulations applicable to this type of formula.
Neither Noobiotik nor our Intimate Flora Probiotic include this vitamin. In regulatory terms, Nutri&Co therefore has an argument that the other two formulas cannot claim.
See also: Alternative to Terravita Intimate Flora Probiotic: the comparison
The weak point: L. crispatus dosed at 6 billion
Lactobacillus crispatus is the dominant strain of a healthy vaginal microbiota. Nutri&Co doses it at 6 billion CFUs for 2 capsules, the lowest concentration of the three compared formulas.
Its L. crispatus CCFM1110 strain comes from the Unibio Lab, based in Shanghai. Nutri&Co transparently displays this information on its product sheet. This is a common industrial choice: few laboratories master the production of this particularly fragile strain.
Intimate Flora Probiotic - Supernutrition
€21.90 per month · 1 capsule per day · 20 billion CFUs
- L. crispatus at 10 billion CFUs, the highest concentration of the three compared formulas
- L. helveticus at 2.5 billion CFUs, absent in Nutri&Co and Noobiotik
- DRcaps® gastro-resistant capsules for targeted intestinal release
- Strains cultivated and analyzed in France, certificates available online
- Vegan formula, free from allergens and controversial additives
Noobiotik Intimate Flora: CFU volume as philosophy
Noobiotik doses its formula at 25 billion CFUs for 2 capsules, the highest volume of the three. Based solely on the number of active bacteria ingested, Noobiotik is the most generous.
Five published strain codes, strains registered in France
Noobiotik publishes all of its strain codes on its product sheet: CNCM I-5095, CIRM-BIA 929, ATCC 53103, CNCM I-5094, ARS #B-3208. These strains are registered with the Pasteur Institute and INRAE, two microorganism libraries recognized by the French health authorities.
The brand announces entirely French cultivation, from strain production to encapsulation. In terms of traceability throughout the supply chain, Noobiotik is the most documented formula of the three.
L. rhamnosus GG: intestinal or vaginal?
The code ATCC 53103 identifies L. rhamnosus GG, also known as LGG®. It is the most studied probiotic strain in the world, with over a thousand scientific publications referenced.
The literature specifically dedicated to oral vaginal health primarily cites a different strain: L. rhamnosus GR-1. GG and GR-1 belong to the same species but have distinct codes and colonization profiles that do not necessarily overlap.
Noobiotik doses L. rhamnosus GG at 5.8 billion CFUs, representing 23% of its formula. This significant proportion is attributed to a strain whose documentation primarily focuses on the intestinal microbiota.
The highest price of the three
At €29.90 per month, Noobiotik is positioned €10 above Nutri&Co and €8 above our Intimate Flora Probiotic. For a three-month course, the difference with Nutri&Co reaches €30. The brand offers decreasing discounts on multi-month packs, which partially reduce this difference.
L. crispatus: the strain underdosed by both formulas
Lactobacillus crispatus dominates the vaginal microbiota of most healthy women. It produces lactic acid and hydrogen peroxide, maintaining vaginal pH below 4.5 4.
Researchers classify vaginal microbiotas into five profiles, Community State Types. CST I, dominated by L. crispatus, is associated with the most stable and protective profile.
Here's how the three formulas dose this strain:
- Nutri&Co: 6 billion CFUs, or 50% of its total formula
- Noobiotik: 7 billion CFUs, or 28% of its total formula
- SuperNutrition: 10 billion CFUs, or 50% of its total formula
Our Intimate Flora Probiotics dose L. crispatus 67% higher than Nutri&Co and 43% higher than Noobiotik. This choice is based on a simple principle: the strain that naturally dominates a healthy vaginal microbiota should dominate the formula.
Noobiotik achieves a higher total volume but allocates this budget across five strains, including the intestinally-oriented L. rhamnosus GG. Nutri&Co does concentrate half of its formula on L. crispatus, but its total volume of 12 billion limits the absolute quantity delivered.
L. helveticus: the strain absent from both references
Lactobacillus helveticus is naturally present in healthy vaginal flora. It is among the strains used in several vaginal probiotic formulations evaluated in a clinical context 5.
Neither Nutri&Co nor Noobiotik include it. Nutri&Co retains L. paracasei Lpc-37 at 2 billion CFUs, while Noobiotik retains L. casei CNCM I-5094 at 3 billion CFUs. These two strains are primarily documented for the intestinal microbiota and digestive immunity.
Our Intimate Flora Probiotic includes L. helveticus at 2.5 billion CFUs. This strain complements the action of L. crispatus in maintaining the balance of the vaginal microbiota.
1 capsule or 2 capsules per day: what the dosage changes
Nutri&Co and Noobiotik both recommend 2 capsules daily, at breakfast. Our Intimate Flora Probiotic is administered as 1 capsule per day.
Over a three-month course, this difference represents 180 capsules versus 90. The regularity of daily intake determines the ability of the strains to durably colonize the microbiota. A simple dosage mechanically reduces the risk of forgetting.
All three formulas use gastro-resistant capsules. Nutri&Co uses a vegetable shell based on hydroxypropyl methylcellulose and pectin, Noobiotik uses Embo Caps® technology, and our Intimate Flora Probiotic uses DRcaps® technology. No direct comparative data allows for establishing superiority between these three technologies.
Nutri&Co and Noobiotik both offer a dosage suitable for adolescents, with one capsule per day from 12 years old for Noobiotik and 14 years old for Nutri&Co.
Which formula to choose depending on your profile?
Nutri&Co is suitable if you prioritize clinical evidence
- You want a formula whose complexes have published and identifiable clinical studies
- Vitamin B2 and its European health claim are important to you
- You are looking for the best monthly price of the three formulas (€19.90)
- You prefer to buy in pharmacies rather than exclusively online
- The volume of customer reviews is a reassuring criterion (1,163 reviews)
Noobiotik is suitable if you prioritize volume and traceability
- You are looking for the highest number of CFUs per dose (25 billion)
- The complete publication of strain codes is a decisive criterion
- An entirely French cultivation of strains is important to you
- You accept a higher monthly budget (€29.90)
Our Intimate Flora Probiotics are suitable if you prioritize L. crispatus
- You want the highest concentration of L. crispatus among the three formulas (10 billion CFUs)
- You are looking for a formula integrating L. helveticus, absent in the other two
- A dosage of 1 capsule per day facilitates your regularity over a long course
- You wish to consult the analysis certificates for each production batch
The three formulas remain compatible with each other. A spacing of one to two hours between doses is sufficient if you wish to combine them. No documented interaction exists between their respective strains.
Frequently Asked Questions
Nutri&Co or Noobiotik: which to choose for intimate flora?
Nutri&Co has patented complexes supported by published clinical studies and vitamin B2, for €19.90 per month. Noobiotik doses 25 billion CFUs and publishes all its strain codes, for €29.90. The choice depends on your priority between clinical evidence and bacterial volume.
What is Nutri&Co's SynbAEctive® complex?
SynbAEctive® Femme and SynbAEctive® Gynelle are two patented complexes from the Italian laboratory SynBalance, combining L. plantarum PBS067, L. rhamnosus LRH020, B. lactis BL050, and L. acidophilus PBS066. They are the subject of clinical studies on recurrent bacterial vaginosis.
Which intimate flora probiotic contains the most L. crispatus?
Among the three compared formulas, our Intimate Flora Probiotic doses L. crispatus at 10 billion CFUs, ahead of Noobiotik (7 billion) and Nutri&Co (6 billion). L. crispatus is the dominant strain of a healthy vaginal microbiota.
Can several intimate flora probiotics be taken at the same time?
The three formulas are compatible. Space doses one to two hours apart. No interaction between their strains is documented. Ask your doctor for advice if you are on parallel treatment.
How long does it take to see effects on intimate flora?
Clinical studies on SynbAEctive® complexes report effects from 14 consecutive days of supplementation. The three brands recommend a course of one to three months. The regularity of daily intake determines the results.
Scientific References
- Chen X, Lu Y, Chen T, Li R. The Female Vaginal Microbiome in Health and Bacterial Vaginosis. Front Cell Infect Microbiol. 2021;11:631972. doi:10.3389/fcimb.2021.631972
- Murina F, Vicariotto F. Evaluation of an Orally Administered Multistrain Probiotic Supplement in Reducing Recurrences Rate of Bacterial Vaginosis: A Clinical and Microbiological Study. Advances in Infectious Diseases. 2019;9(3):151-161.
- Vicariotto F, Malfa P, Viciani E, et al. Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial. Nutrients. 2024;16(3):402. doi:10.3390/nu16030402
- Gupta S, Kakkar V, Bhushan I. Crosstalk between Vaginal Microbiome and Female Health: A review. Microb Pathog. 2019;136:103696. doi:10.1016/j.micpath.2019.103696
- Presence of L. helveticus in vaginal probiotic formulations evaluated in clinical trials (Ecologic Femi+, Winclove Probiotics) — precise reference to be confirmed before publication (source to be verified)
This article is for informational purposes only. Dietary supplements are not medicines and do not replace medical advice. In case of persistent or recurrent symptoms, consult your doctor or gynecologist. Prices noted in July 2026, subject to change.
Safety advice
Before starting any treatment, consult your doctor.
