Magnesium Bisglycinate

A course of magnesium supplements aims to address a deficiency often caused by stress or a modern diet. It helps reduce fatigue, irritability, and muscle tension (cramps). It is a key support for restoring restful sleep and a calmer nervous system.

For more information, check out our guide on why and how to take magnesium .

Here are 7 major benefits of magnesium proven by science:

• Fatigue reduction
• Nervous system support and stress management
• Cramp prevention and muscle support
• Sleep improvement
• Bone health
• Blood pressure regulation and cardiovascular health
• Blood sugar regulation aid

Scientific sources:

• The effect of magnesium supplementation on primary insomnia in elderly”, 2012, https://pubmed.ncbi.nlm.nih.gov/23853635/
• Magnesium supplementation in pregnancy”, 2014, https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000937.pub2/full
• “Magnesium and Muscle Performance in Older Adults,” 2019, https://www.mdpi.com/2072-6643/11/2/364.
• “Scientific Opinion on the substantiation of health claims related to magnesium”, https://www.efsa.europa.eu/en/efsajournal/pub/1216

Are you wondering about the time it takes for magnesium to work? The first benefits can be felt in a few days , but it takes about 2 to 4 weeks for a course of treatment to produce lasting effects.

Here are the key points to remember:

• Rapid effects (a few hours to a few days): relief from muscle cramps and a feeling of relaxation facilitating sleep.
• Intermediate effects (1 to 4 weeks): noticeable reduction in stress, anxiety and overall fatigue.
• Prolonged effects (beyond 1 month): replenishment of reserves, deep support of the nervous system and bone strength.

The most common signs are physical and neurological. Think of unexplained fatigue, muscle cramps, or the dreaded eyelid twitch.

On a mental level, increased anxiety, greater irritability, and disturbed sleep are frequent warning signs. These symptoms often act in concert.

Yes. The main contraindication is severe renal insufficiency . Since magnesium is eliminated by the kidneys, impaired kidney function can lead to an accumulation of this mineral in the body (hypermagnesemia).

If you suffer from kidney disease , you must consult your doctor before taking any supplements. Similarly, this product is not recommended for people suffering from myasthenia gravis .

The effectiveness of our Magnesium rests on two scientific pillars: the Bisglycinate form (chelation) and the synergy with active Vitamin B6 (P-5-P) . Here are the reference studies that validate our formulation:

• Superior bioavailability: Unlike classic salts (oxide, chloride), bisglycinate is a chelated form that uses dipeptide transporters in the intestine, allowing much higher absorption by the body (Source: https://pubmed.ncbi.nlm.nih.gov/11794633/).
• Total digestive tolerance: Clinical research demonstrates that bisglycinate does not cause laxative effects, as it is stable and does not create water retention in the intestines, unlike low-grade magnesium (Source: https://www.mdpi.com/2072-6643/16/24/4367).
• Increased effectiveness against stress: A major study has proven that the combination of Magnesium + Vitamin B6 is 24% more effective than magnesium alone in reducing the symptoms of severe stress (Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC6298677/).

According to the SU.VI.MAX study, nearly 75% of men and 77% of women have intakes below the recommended daily allowance (RDA). Magnesium can be taken year-round as a preventative measure, particularly by athletes. A minimum 3-month course is recommended.

Vitamin B6 is involved in the synthesis of neurotransmitters such as serotonin (sleep, mood) and in maintaining a balanced nervous system. It also helps increase magnesium absorption.

Yes, the combination is even highly recommended for optimal effectiveness.

Magnesium + Vitamin D Synergy: Magnesium is essential for activating Vitamin D in the blood. Without sufficient magnesium intake, your Vitamin D supplementation is less effective.

Synergy with Vitamin B6: Our formula already contains bioactive Vitamin B6 (P5P) to facilitate the entry of magnesium into the cell.

To avoid: Avoid taking it simultaneously with iron or high doses of calcium, as they may compete during intestinal absorption.

Unlike marine magnesium (oxide), which is poorly absorbed and can have a laxative effect, bisglycinate is bound to an amino acid (glycine). This ensures maximum absorption by cells and perfect digestive tolerance, without intestinal discomfort.

No, magnesium does not cause weight gain. On the contrary, it plays a key role in carbohydrate metabolism and insulin regulation.

• Calories: A magnesium supplement provides a caloric value close to zero.
• Weight management: By helping to reduce stress (cortisol) and improve sleep quality, it can indirectly facilitate weight management and limit emotional snacking.
• Water retention: Contrary to some misconceptions, it helps with electrolyte balance, which is beneficial against water retention.

Yes, because it promotes nervous and muscular relaxation. Bisglycinate is particularly recommended before bedtime.

Source 2025: https://www.wbcil.com/blog/the-glycine-advantage-how-new-pubmed-research-reveals-magnesium-bisglycinates-untapped-potential/

Athletes lose magnesium through sweat. It is crucial for preventing cramps and optimizing recovery.

Yes. Many brands sell magnesium labeled 'bisglycinate' which is actually mixed with magnesium oxide (cheaper) to increase the percentage of pure magnesium. Ours is 100% pure bisglycinate, with no hidden additives.

Stress depletes magnesium reserves, creating a vicious cycle. A course of treatment helps regulate cortisol.

All our food supplements are manufactured in France by an ISO 22000 certified laboratory. All raw materials are inspected and analyzed. We provide you with certificates of analysis that attest to the quality of our products.

Our magnesium supplement contains no allergens such as soy, gluten, lactose, or eggs. It is suitable for vegans.

The major difference lies in the chemical form and purity . Most supplements sold in pharmacies use magnesium oxide or magnesium citrate (which is less expensive).

• Bioavailability: Our Bisglycinate (chelated) form is absorbed at a rate of 80% by the body, compared to only 4 to 20% for conventional pharmacy forms.
• Digestive comfort: Unlike pharmacy magnesium, which is often laxative, bisglycinate is perfectly tolerated by sensitive intestines.
• 100% Unbuffered: Unlike many commercial products, we do not add hidden oxides to artificially "inflate" the elemental magnesium content.

Pullulan capsules are sought after by the most discerning consumers, who are looking for a more natural product. Pullulan is a natural polysaccharide made from tapioca starch. It is guaranteed to be free of chemicals, solvents, preservatives, and allergens.